PP-K9218-00

antibody from R&D Systems

Targeting: HNF4A HNF4, MODY, MODY1, NR2A1, TCF14

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

PP-K9218-00

Provider

R&D Systems

Product name

Human HNF-4 alpha/NR2A1 Antibody

Antibody type

Monoclonal

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

K9218

Vial size

100 ug

Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

References

Submitted references

TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors.

Ancey PB, Ecsedi S, Lambert MP, Talukdar FR, Cros MP, Glaise D, Narvaez DM, Chauvet V, Herceg Z, Corlu A, Hernandez-Vargas H
Stem cell reports 2017 Jul 11;9(1):264-278

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Genomic variants link to hepatitis C racial disparities.

Yeh MM, Boukhar S, Roberts B, Dasgupta N, Daoud SS
Oncotarget 2017 Aug 29;8(35):59455-59475

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Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.

Saha SK, Parachoniak CA, Ghanta KS, Fitamant J, Ross KN, Najem MS, Gurumurthy S, Akbay EA, Sia D, Cornella H, Miltiadous O, Walesky C, Deshpande V, Zhu AX, Hezel AF, Yen KE, Straley KS, Travins J, Popovici-Muller J, Gliser C, Ferrone CR, Apte U, Llovet JM, Wong KK, Ramaswamy S, Bardeesy N
Nature 2014 Sep 4;513(7516):110-4

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Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling.

Fabris L, Cadamuro M, Guido M, Spirli C, Fiorotto R, Colledan M, Torre G, Alberti D, Sonzogni A, Okolicsanyi L, Strazzabosco M
The American journal of pathology 2007 Aug;171(2):641-53