Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Flow cytometry [1]
- Other assay [5]
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Validation data
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- Product number
- MHCD0412 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD4 Monoclonal Antibody (S3.5), PE-Cyanine7
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- The R-phycoerythrin (PE)-Cy7® tandem conjugate permits simultaneous multicolor labeling and detection of multiple targets with excitation by a 488 nm laser without occupying traditional channels associated with FITC and PE.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- S3.5
- Vial size
- 500 µL
- Storage
- 4° C, store in dark
Submitted references Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis.
Increased ratio of Th17 cells to SIGIRR(+)CD4(+) T cells in peripheral blood of patients with SLE is associated with disease activity.
A novel method for assaying human regulatory T cell direct suppression of B cell effector function.
Regulatory T cells and human myeloid dendritic cells promote tolerance via programmed death ligand-1.
Apoptosis of CD4(+)CD25(high) T cells in response to Sirolimus requires activation of T cell receptor and is modulated by IL-2.
A phase I/II study of a MUC1 peptide pulsed autologous dendritic cell vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors.
Sun M, Wu W, Chen L, Yang W, Huang X, Ma C, Chen F, Xiao Y, Zhao Y, Ma C, Yao S, Carpio VH, Dann SM, Zhao Q, Liu Z, Cong Y
Nature communications 2018 Sep 3;9(1):3555
Nature communications 2018 Sep 3;9(1):3555
Increased ratio of Th17 cells to SIGIRR(+)CD4(+) T cells in peripheral blood of patients with SLE is associated with disease activity.
Xiao JP, Wang DY, Wang XR, Yuan L, Hao L, Wang DG
Biomedical reports 2018 Oct;9(4):339-344
Biomedical reports 2018 Oct;9(4):339-344
A novel method for assaying human regulatory T cell direct suppression of B cell effector function.
Weingartner E, Courneya JP, Keegan A, Golding A
Journal of immunological methods 2017 Feb;441:1-7
Journal of immunological methods 2017 Feb;441:1-7
Regulatory T cells and human myeloid dendritic cells promote tolerance via programmed death ligand-1.
Amarnath S, Costanzo CM, Mariotti J, Ullman JL, Telford WG, Kapoor V, Riley JL, Levine BL, June CH, Fong T, Warner NL, Fowler DH
PLoS biology 2010 Feb 2;8(2):e1000302
PLoS biology 2010 Feb 2;8(2):e1000302
Apoptosis of CD4(+)CD25(high) T cells in response to Sirolimus requires activation of T cell receptor and is modulated by IL-2.
Molhoek KR, McSkimming CC, Olson WC, Brautigan DL, Slingluff CL Jr
Cancer immunology, immunotherapy : CII 2009 Jun;58(6):867-76
Cancer immunology, immunotherapy : CII 2009 Jun;58(6):867-76
A phase I/II study of a MUC1 peptide pulsed autologous dendritic cell vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors.
Lepisto AJ, Moser AJ, Zeh H, Lee K, Bartlett D, McKolanis JR, Geller BA, Schmotzer A, Potter DP, Whiteside T, Finn OJ, Ramanathan RK
Cancer therapy 2008;6(B):955-964
Cancer therapy 2008;6(B):955-964
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were stained using PE-Cy®7 of anti-human CD4 monoclonal antibody (clone S3.5). The negative control profiles represent unstained cells.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL