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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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Validation data
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- Product number
- orb11613 - Provider product page
- Provider
- Biorbyt
- Product name
- E-Cadherin antibody
- Antibody type
- Polyclonal
- Description
- Goat polyclonal to CDH1. CDH1 is a classical member of the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised consists of 5 cadherin repeats in the extracellular domain, one transmembrane domain, and a and a highly conserved intracellular domain that binds b-catenin and p120-catenin. CDH1 is involved in mechanisms regulating proliferation, mobility and cell-cell adhesions of epithelial cells. Loss of E-cadherin function or expression has been implicated in cancer metastasis and progression.
- Reactivity
- Human, Mouse, Rat, Canine, Simian
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 μg
- Concentration
- 1 mg per ml
- Storage
- Store at -20 °C. for long term storage and 2-8 °C. for up to one month.Avoid freeze/thaw cycles.
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Supportive validation
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- Biorbyt (provider)
- Main image
- Experimental details
- Western blot analysis of AtT-20 cell lysate using E-Cadherin antibody
- Other comments
- Specificity: Detects endogenous levels of total E-cadherin protein by Western blot in the whole cell lysates (COS-7 and MDCK).
