NBP2-48120

antibody from Novus Biologicals
Targeting: AFP FETA, HPAFP
Provider product page for NBP2-48120

Antibody data

Product number
NBP2-48120 - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal alpha-Fetoprotein/AFP Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. The yolk sac and the liver produce AFP during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spinal bifida and anencephaly.
Reactivity
Human
Host
Mouse
Isotype
IgG
Vial size
7 ml
Storage
Store at 4C.
AFP protein structure - NBP2-48120 shown in red.