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- Product number
- MAB21091 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse IL-27 R alpha/WSX-1/TCCR Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse IL-27 R alpha/WSX-1/TCCR in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse gp130 or recombinant human IL-27 R alpha is observed.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
O70394- Isotype
- IgG
- Antibody clone number
- 263503
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39.
Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor.
Mascanfroni ID, Yeste A, Vieira SM, Burns EJ, Patel B, Sloma I, Wu Y, Mayo L, Ben-Hamo R, Efroni S, Kuchroo VK, Robson SC, Quintana FJ
Nature immunology 2013 Oct;14(10):1054-63
Nature immunology 2013 Oct;14(10):1054-63
Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor.
Pradhan A, Lambert QT, Reuther GW
Proceedings of the National Academy of Sciences of the United States of America 2007 Nov 20;104(47):18502-7
Proceedings of the National Academy of Sciences of the United States of America 2007 Nov 20;104(47):18502-7
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