DPAB-DC3234

ZYX antibody from Creative Diagnostics
Western blot
Recommended by provider
ELISA
Recommended by provider

Antibody data

Product number
DPAB-DC3234
Provider
Creative Diagnostics
Proper citation
Creative Diagnostics Cat#DPAB-DC3234, RRID:AB_2500499
Product name
Anti-ZYX (internal region) polyclonal antibody
Provider product page
Creative Diagnostics - DPAB-DC3234
Antibody type
Polyclonal
Description
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
Reactivity
Human
Host
Goat
Conjugate
Unconjugated
Vial size
100  mg
Concentration
0.5  mg/ml
Storage
store at -20°CAliquot to avoid repeated freezing and thawing.
Handling
The antibody solution should be gently mixed before use.
Provider Type Product Number
- No reagents -