orb137858

antibody from Biorbyt

Targeting: HOXA1 HOX1, HOX1F

Western blot (Recommended by provider)

Antibody Data

Product number

orb137858

Provider

Biorbyt

Product name

HOXA1 antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to HOXA1. HOXA1 (HOMEOBOX A1), also called HOMEOBOX 1F, is a protein that in humans is encoded by the HOXA1 gene. In PA-1 teratocarcinoma cells, HOXA1 was induced by retinoic acid earlier than other HOXA cluster genes.The HOXA1 gene is mapped on 7p15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. A common polymorphism in the HOXA1 gene is associated with a susceptibility to autism spectrum disorder. Three-dimensional reconstructions of Hoxa1 -/- rhombencephalon revealed that it bears only 5 rhombomeric structures instead of the normal 7. A single maternal administration of a low dose of the vitamin A metabolite retinoic acid was sufficient to compensate the requirement for Hoxa1 function in Hoxa1-deficient mice.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 μg

Storage

Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.