BS60991

antibody from Bioworld Technology, Inc
Targeting: BCL6 BCL5, BCL6A, LAZ3, ZBTB27, ZNF51
Provider product page for BS60991

Antibody data

Product number
BS60991 - Provider product page
Provider
Bioworld Technology, Inc
Product name
BCL6 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human BCL6.
Description
Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and Th1/Th2 differentiation. Bcl-6 negatively regulates NFkB expression, thereby inhibiting NFkB-mediated cellular functions. HDAC- and silent information regulator (SIR)-2-dependent acet-ylation of Bcl-6 causes downregulation of activity by inhibiting the ability of Bcl-6 to recruit complexes containing histone deacetylases (HDACs). Bcl-6 is frequently deregulated in non-Hodgkin£ªs B cell lymphomas. The human BCL6 gene has been shown to encode a protein of 706 amino acids.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BCL6 protein structure - BS60991 shown in red.