Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN350849 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350849, RRID:AB_10781379
- Product name
- anti-Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the c-terminal of Sodium channel protein type 1 subunit alpha (SCN1A, Nav1.1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologus in rat and human.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 500 μg
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Elicited repetitive daily blindness: a new phenotype associated with hemiplegic migraine and SCN1A mutations.
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2.
Localization of a putative human brain sodium channel gene (SCN1A) to chromosome band 2q24.
Differential expression of two sodium channel subtypes in human brain.
Vahedi K, Depienne C, Le Fort D, Riant F, Chaine P, Trouillard O, Gaudric A, Morris MA, Leguern E, Tournier-Lasserve E, Bousser MG
Neurology 2009 Mar 31;72(13):1178-83
Neurology 2009 Mar 31;72(13):1178-83
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
Hillier LW, Graves TA, Fulton RS, Fulton LA, Pepin KH, Minx P, Wagner-McPherson C, Layman D, Wylie K, Sekhon M, Becker MC, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Kremitzki C, Oddy L, Du H, Sun H, Bradshaw-Cordum H, Ali J, Carter J, Cordes M, Harris A, Isak A, van Brunt A, Nguyen C, Du F, Courtney L, Kalicki J, Ozersky P, Abbott S, Armstrong J, Belter EA, Caruso L, Cedroni M, Cotton M, Davidson T, Desai A, Elliott G, Erb T, Fronick C, Gaige T, Haakenson W, Haglund K, Holmes A, Harkins R, Kim K, Kruchowski SS, Strong CM, Grewal N, Goyea E, Hou S, Levy A, Martinka S, Mead K, McLellan MD, Meyer R, Randall-Maher J, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Shah N, Swearengen-Shahid S, Snider J, Strong JT, Thompson J, Yoakum M, Leonard S, Pearman C, Trani L, Radionenko M, Waligorski JE, Wang C, Rock SM, Tin-Wollam AM, Maupin R, Latreille P, Wendl MC, Yang SP, Pohl C, Wallis JW, Spieth J, Bieri TA, Berkowicz N, Nelson JO, Osborne J, Ding L, Meyer R, Sabo A, Shotland Y, Sinha P, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Jones TA, She X, Ciccarelli FD, Izaurralde E, Taylor J, Schmutz J, Myers RM, Cox DR, Huang X, McPherson JD, Mardis ER, Clifton SW, Warren WC, Chinwalla AT, Eddy SR, Marra MA, Ovcharenko I, Furey TS, Miller W, Eichler EE, Bork P, Suyama M, Torrents D, Waterston RH, Wilson RK
Nature 2005 Apr 7;434(7034):724-31
Nature 2005 Apr 7;434(7034):724-31
Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2.
Escayg A, MacDonald BT, Meisler MH, Baulac S, Huberfeld G, An-Gourfinkel I, Brice A, LeGuern E, Moulard B, Chaigne D, Buresi C, Malafosse A
Nature genetics 2000 Apr;24(4):343-5
Nature genetics 2000 Apr;24(4):343-5
Localization of a putative human brain sodium channel gene (SCN1A) to chromosome band 2q24.
Malo MS, Blanchard BJ, Andresen JM, Srivastava K, Chen XN, Li X, Jabs EW, Korenberg JR, Ingram VM
Cytogenetics and cell genetics 1994;67(3):178-86
Cytogenetics and cell genetics 1994;67(3):178-86
Differential expression of two sodium channel subtypes in human brain.
Lu CM, Han J, Rado TA, Brown GB
FEBS letters 1992 May 25;303(1):53-8
FEBS letters 1992 May 25;303(1):53-8
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