NBP2-47965PE

antibody from Novus Biologicals

Targeting: NGFR CD271, p75NTR, TNFRSF16

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

NBP2-47965PE

Provider

Novus Biologicals

Product name

Mouse Monoclonal NGFR/TNFRSF16/p75NTR Antibody

Antibody type

Monoclonal

Description

Protein A or G purified. It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.

Reactivity

Human, Mouse, Rat, Feline, Rabbit, Simian

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.