MAB3050

antibody from R&D Systems

Targeting: ITGAV CD51, MSK8, VNRA, VTNR

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

MAB3050

Provider

R&D Systems

Product name

Human Integrin alpha V beta 3 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human Integrin alpha V beta 3.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

23C6

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Acidic preconditioning of endothelial colony-forming cells (ECFC) promote vasculogenesis under proinflammatory and high glucose conditions in vitro and in vivo.

Mena HA, Zubiry PR, Dizier B, Schattner M, Boisson-Vidal C, Negrotto S
Stem cell research & therapy 2018 May 2;9(1):120

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Osteopontin-integrin engagement induces HIF-1α-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer.

Fan CS, Chen WS, Chen LL, Chen CC, Hsu YT, Chua KV, Wang HD, Huang TS
Oncotarget 2018 Jan 12;9(4):4998-5015

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HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection.

Jin YP, Valenzuela NM, Zhang X, Rozengurt E, Reed EF
Journal of immunology (Baltimore, Md. : 1950) 2018 Apr 1;200(7):2372-2390

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AlphaVBeta3 Integrin expression within uterine endometrium in unexplained infertility: a prospective cohort study.

Elnaggar A, Farag AH, Gaber ME, Hafeez MA, Ali MS, Atef AM
BMC women's health 2017 Sep 26;17(1):90

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cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells.

Miyano K, Cabral H, Miura Y, Matsumoto Y, Mochida Y, Kinoh H, Iwata C, Nagano O, Saya H, Nishiyama N, Kataoka K, Yamasoba T
Journal of controlled release : official journal of the Controlled Release Society 2017 Sep 10;261:275-286

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Arachidonic acid and docosahexaenoic acid suppress osteoclast formation and activity in human CD14+ monocytes, in vitro.

Kasonga AE, Deepak V, Kruger MC, Coetzee M
PloS one 2015;10(4):e0125145

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Osteopontin Promotes Oncostatin M Production in Human Osteoblasts: Implication of Rheumatoid Arthritis Therapy.

Su CM, Chiang YC, Huang CY, Hsu CJ, Fong YC, Tang CH
Journal of immunology (Baltimore, Md. : 1950) 2015 Oct 1;195(7):3355-64

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C6-ceramide nanoliposome suppresses tumor metastasis by eliciting PI3K and PKCζ tumor-suppressive activities and regulating integrin affinity modulation.

Zhang P, Fu C, Hu Y, Dong C, Song Y, Song E
Scientific reports 2015 Mar 20;5:9275

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Mesenchymal stem cell contact promotes CCN1 splicing and transcription in myeloma cells.

Dotterweich J, Ebert R, Kraus S, Tower RJ, Jakob F, Schütze N
Cell communication and signaling : CCS 2014 Jun 25;12:36

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The nexus between VEGF and NFκB orchestrates a hypoxia-independent neovasculogenesis.

DeNiro M, Al-Mohanna FH, Alsmadi O, Al-Mohanna FA
PloS one 2013;8(3):e59021

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The role of RGD-tagged helical rosette nanotubes in the induction of inflammation and apoptosis in human lung adenocarcinoma cells through the P38 MAPK pathway.

Suri SS, Rakotondradany F, Myles AJ, Fenniri H, Singh B
Biomaterials 2009 Jun;30(17):3084-90