NBP2-54432-100ug

antibody from Novus Biologicals

Targeting: ITGAX CD11C

Immunocytochemistry

Flow cytometry

Protein array

Antibody data

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Validation data

Product number: NBP2-54432-100ug - Provider product page
Provider: Novus Biologicals
Product name: Mouse Monoclonal CD11c Antibody
Antibody type: Monoclonal
Description: Protein A or G purified. Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues
Reactivity: Human
Host: Mouse
Isotype: IgG
Vial size: 100 ug
Concentration: 1 mg/ml
Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.

ITGAX protein structure - NBP2-54432-100ug shown in red.