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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations [0]
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- Product number
- ABIN238446 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Integrin beta 2 (ITGB2) (Activation Site) antibody (APC)
- Antibody type
- Monoclonal
- Description
- Size-exclusion chromatography.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- Activation Site
- Isotype
- IgG
- Antibody clone number
- MEM-148
- Vial size
- 100 tests
- Storage
- Store the antibody at 2-8°C for one month or at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The virological synapse facilitates herpes simplex virus entry into T cells.
Monomeric expression of bovine beta2-integrin subunits reveals their role in Mannheimia haemolytica leukotoxin-induced biological effects.
CD18 in monogenic and polygenic inflammatory processes of the skin.
Distinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2.
CD4+ T cell-associated pathophysiology critically depends on CD18 gene dose effects in a murine model of psoriasis.
A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.
A novel anti-CD18 mAb recognizes an activation-related epitope and induces a high-affinity conformation in leukocyte integrins.
Contribution of CD11a/CD18, CD11b/CD18, ICAM-1 (CD54) and -2 (CD102) to human monocyte migration through endothelium and connective tissue fibroblast barriers.
Mac-1 (CD11b/CD18) is the predominant beta 2 (CD18) integrin mediating human neutrophil migration through synovial and dermal fibroblast barriers.
Aubert M, Yoon M, Sloan DD, Spear PG, Jerome KR
Journal of virology 2009 Jun;83(12):6171-83
Journal of virology 2009 Jun;83(12):6171-83
Monomeric expression of bovine beta2-integrin subunits reveals their role in Mannheimia haemolytica leukotoxin-induced biological effects.
Dassanayake RP, Maheswaran SK, Srikumaran S
Infection and immunity 2007 Oct;75(10):5004-10
Infection and immunity 2007 Oct;75(10):5004-10
CD18 in monogenic and polygenic inflammatory processes of the skin.
Peters T, Sindrilaru A, Wang H, Oreshkova T, Renkl AC, Kess D, Scharffetter-Kochanek K
The journal of investigative dermatology. Symposium proceedings 2006 Sep;11(1):7-15
The journal of investigative dermatology. Symposium proceedings 2006 Sep;11(1):7-15
Distinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2.
Solovjov DA, Pluskota E, Plow EF
The Journal of biological chemistry 2005 Jan 14;280(2):1336-45
The Journal of biological chemistry 2005 Jan 14;280(2):1336-45
CD4+ T cell-associated pathophysiology critically depends on CD18 gene dose effects in a murine model of psoriasis.
Kess D, Peters T, Zamek J, Wickenhauser C, Tawadros S, Loser K, Varga G, Grabbe S, Nischt R, Sunderkötter C, Müller W, Krieg T, Scharffetter-Kochanek K
Journal of immunology (Baltimore, Md. : 1950) 2003 Dec 1;171(11):5697-706
Journal of immunology (Baltimore, Md. : 1950) 2003 Dec 1;171(11):5697-706
A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.
Drbal K, Angelisová P, Hilgert I, Cerný J, Novák P, Horejsí V
Blood 2001 Sep 1;98(5):1561-6
Blood 2001 Sep 1;98(5):1561-6
A novel anti-CD18 mAb recognizes an activation-related epitope and induces a high-affinity conformation in leukocyte integrins.
Drbal K, Angelisová P, Cerný J, Hilgert I, Horejsí V
Immunobiology 2001 May;203(4):687-98
Immunobiology 2001 May;203(4):687-98
Contribution of CD11a/CD18, CD11b/CD18, ICAM-1 (CD54) and -2 (CD102) to human monocyte migration through endothelium and connective tissue fibroblast barriers.
Shang XZ, Issekutz AC
European journal of immunology 1998 Jun;28(6):1970-9
European journal of immunology 1998 Jun;28(6):1970-9
Mac-1 (CD11b/CD18) is the predominant beta 2 (CD18) integrin mediating human neutrophil migration through synovial and dermal fibroblast barriers.
Gao JX, Issekutz AC
Immunology 1996 Jul;88(3):463-70
Immunology 1996 Jul;88(3):463-70
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