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- Product number
- ABIN1673470 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence at the C-terminal of human CRTC1, different from the related rat and mouse sequences by two amino acids.Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.
TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity.
Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A
Nature 2011 Feb 17;470(7334):404-8
Nature 2011 Feb 17;470(7334):404-8
TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity.
Kovács KA, Steullet P, Steinmann M, Do KQ, Magistretti PJ, Halfon O, Cardinaux JR
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 13;104(11):4700-5
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 13;104(11):4700-5
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