ABIN2838108

antibody from antibodies-online

Targeting: UPF1 HUPF1, KIAA0221, NORF1, pNORF1, RENT1, smg-2

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN2838108

Provider

antibodies-online

Product name

anti-UPF1 Regulator of Nonsense Transcripts Homolog (Yeast) (UPF1) (AA 297-326), (N-Term) antibody

Antibody type

Polyclonal

Description

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

AA 297-326, N-Term

Antibody clone number

RB8352

Vial size

80 μL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Submitted references

Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X.

Kang JQ, Shen W, Macdonald RL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Mar 4;29(9):2833-44

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Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.

Ohnishi T, Yamashita A, Kashima I, Schell T, Anders KR, Grimson A, Hachiya T, Hentze MW, Anderson P, Ohno S
Molecular cell 2003 Nov;12(5):1187-200

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Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts.

Mendell JT, ap Rhys CM, Dietz HC
Science (New York, N.Y.) 2002 Oct 11;298(5592):419-22

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB