MAB2037

antibody from R&D Systems

Targeting: C5 C5a, C5b, CPAMD4

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB2037

Provider

R&D Systems

Product name

Anti-Human Complement Component C5/C5a Monoclonal Antibody (Clone 295003)

Antibody type

Monoclonal

Antigen

E. coli-derived recombinant human Complement Component C5a, Thr678-Arg751

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human

Host

Mouse

Antigen sequence

P01031


Isotype

IgG

Vial size

500 µg

References

Submitted references

Attenuation of Staphylococcus aureus-Induced Bacteremia by Human Mini-Antibodies Targeting the Complement Inhibitory Protein Efb.

Georgoutsou-Spyridonos M, Ricklin D, Pratsinis H, Perivolioti E, Pirmettis I, Garcia BL, Geisbrecht BV, Foukas PG, Lambris JD, Mastellos DC, Sfyroera G
Journal of immunology (Baltimore, Md. : 1950) 2015 Oct 15;195(8):3946-58

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Generation of multiple fluid-phase C3b:plasma protein complexes during complement activation: possible implications in C3 glomerulopathies.

Ramadass M, Ghebrehiwet B, Smith RJ, Kew RR
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 1;192(3):1220-30

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C5a and TNF-alpha up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrome.

Kambas K, Markiewski MM, Pneumatikos IA, Rafail SS, Theodorou V, Konstantonis D, Kourtzelis I, Doumas MN, Magotti P, Deangelis RA, Lambris JD, Ritis KD
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7368-75

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C5a and TNF-alpha up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrome.

Kambas K, Markiewski MM, Pneumatikos IA, Rafail SS, Theodorou V, Konstantonis D, Kourtzelis I, Doumas MN, Magotti P, Deangelis RA, Lambris JD, Ritis KD
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7368-75