ABIN405980

antibody from antibodies-online

Targeting: IDH2

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN405980

Provider

antibodies-online

Product name

anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (Middle Region) antibody

Antibody type

Polyclonal

Antigen

The immunogen for anti-IDH2 antibody: synthetic peptide directed towards the middle region of human IDH2

Description

Affinity Purified

Reactivity

Human, Mouse, Rat, Bovine, Chicken/Avian, Xenopus, Zebrafish

Host

Rabbit

Antigen sequence

GGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQ
YKATD FVADRAGTFK


Epitope

Middle Region

Vial size

50 μg

Concentration

1mg/mL

Storage

-20°C

Handling

Avoid repeated freeze-thaw cycles.

References

Submitted references

Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferation.

Vohwinkel CU, Lecuona E, Sun H, Sommer N, Vadász I, Chandel NS, Sznajder JI
The Journal of biological chemistry 2011 Oct 28;286(43):37067-76

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Silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase by small interfering RNA enhances heat shock-induced apoptosis.

Shin SW, Kil IS, Park JW
Biochemical and biophysical research communications 2008 Feb 22;366(4):1012-8