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- References [2]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN359330 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-PDZ Binding Kinase (PBK) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the C-terminal region of human PBK.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1 mg
- Concentration
- 0.25 mg/ml
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Submitted references Protein expression of PDZ-binding kinase is up-regulated in hematologic malignancies and strongly down-regulated during terminal differentiation of HL-60 leukemic cells.
PBK/TOPK is a novel mitotic kinase which is upregulated in Burkitt's lymphoma and other highly proliferative malignant cells.
Nandi A, Tidwell M, Karp J, Rapoport AP
Blood cells, molecules & diseases 2004 Jan-Feb;32(1):240-5
Blood cells, molecules & diseases 2004 Jan-Feb;32(1):240-5
PBK/TOPK is a novel mitotic kinase which is upregulated in Burkitt's lymphoma and other highly proliferative malignant cells.
Simons-Evelyn M, Bailey-Dell K, Toretsky JA, Ross DD, Fenton R, Kalvakolanu D, Rapoport AP
Blood cells, molecules & diseases 2001 Sep-Oct;27(5):825-9
Blood cells, molecules & diseases 2001 Sep-Oct;27(5):825-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of PBK (arrow) using rabbit polyclonal PBK Antibody
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human testis tissue reacted with PBK Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
