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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PA5-19080 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- PXR Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Role of c-Jun-N-Terminal Kinase in Pregnane X Receptor-Mediated Induction of Human Cytochrome P4503A4 In Vitro.
Celastrol regulates multiple nuclear transcription factors belonging to HSP90's clients in a dose- and cell type-dependent way.
Taneja G, Chu C, Maturu P, Moorthy B, Ghose R
Drug metabolism and disposition: the biological fate of chemicals 2018 Apr;46(4):397-404
Drug metabolism and disposition: the biological fate of chemicals 2018 Apr;46(4):397-404
Celastrol regulates multiple nuclear transcription factors belonging to HSP90's clients in a dose- and cell type-dependent way.
Zhang D, Xu L, Cao F, Wei T, Yang C, Uzan G, Peng B
Cell stress & chaperones 2010 Nov;15(6):939-46
Cell stress & chaperones 2010 Nov;15(6):939-46
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western Blot staining of HepG2 cell lysate using Product # PA5-19080 at a concentration of 1.0 µg/mL, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of PXR in Human Small Intestine using a PXR monoclonal antibody (Product #PA5-19080) at 3.75 µg/mL. The Human Small Intestine tissue section was paraffin embeded and detected using steamed antigen retrieval with citrate buffer pH 6, AP-staining.
