PAB2978

antibody from Abnova Corporation

Targeting: YARS1 tyrRS, YARS, YRS, YTS

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB2978

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB2978, RRID:AB_1581971

Product name

YARS polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of YARS.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Gain-of-function mutational activation of human tRNA synthetase procytokine.

Yang XL, Kapoor M, Otero FJ, Slike BM, Tsuruta H, Frausto R, Bates A, Ewalt KL, Cheresh DA, Schimmel P
Chemistry & biology 2007 Dec;14(12):1323-33

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Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy.

Jordanova A, Irobi J, Thomas FP, Van Dijck P, Meerschaert K, Dewil M, Dierick I, Jacobs A, De Vriendt E, Guergueltcheva V, Rao CV, Tournev I, Gondim FA, D'Hooghe M, Van Gerwen V, Callaerts P, Van Den Bosch L, Timmermans JP, Robberecht W, Gettemans J, Thevelein JM, De Jonghe P, Kremensky I, Timmerman V
Nature genetics 2006 Feb;38(2):197-202

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Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS.

Bonnefond L, Fender A, Rudinger-Thirion J, Giegé R, Florentz C, Sissler M
Biochemistry 2005 Mar 29;44(12):4805-16

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Formalin-fixed and paraffin-embedded human lung carcinomareacted with YARS polyclonal antibody (Cat # PAB2978), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)