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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- PAB11975 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB11975, RRID:AB_1717252
- Product name
- ZMPSTE24 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of ZMPSTE24.
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells.
Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis.
Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24.
Coffinier C, Hudon SE, Farber EA, Chang SY, Hrycyna CA, Young SG, Fong LG
Proceedings of the National Academy of Sciences of the United States of America 2007 Aug 14;104(33):13432-7
Proceedings of the National Academy of Sciences of the United States of America 2007 Aug 14;104(33):13432-7
Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis.
Young SG, Fong LG, Michaelis S
Journal of lipid research 2005 Dec;46(12):2531-58
Journal of lipid research 2005 Dec;46(12):2531-58
Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24.
Corrigan DP, Kuszczak D, Rusinol AE, Thewke DP, Hrycyna CA, Michaelis S, Sinensky MS
The Biochemical journal 2005 Apr 1;387(Pt 1):129-38
The Biochemical journal 2005 Apr 1;387(Pt 1):129-38
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of ZMPSTE24 in human testis with ZMPSTE24 polyclonal antibody (Cat # PAB11975).
