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- Antibody Data
- Antigen structure
- References [21]
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- Product number
- BAF421 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse IL-17 Biotinylated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse IL-17 in ELISAs and Western blots. In sandwich immunoassays, less than 0.05% cross-reactivity with recombinant human IL-17 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Biotin
- Antigen sequence
Q62386- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3.
The Major Histocompatibility Complex Class III Haplotype Ltab-Ncr3 Regulates Adjuvant-Induced but Not Antigen-Induced Autoimmunity.
MHC class II alleles associated with Th1 rather than Th17 type immunity drive the onset of early arthritis in a rat model of rheumatoid arthritis.
Interferon-gamma regulates inflammatory cell death by targeting necroptosis in experimental autoimmune arthritis.
Enhanced immunoregulation of mesenchymal stem cells by IL-10-producing type 1 regulatory T cells in collagen-induced arthritis.
Interferon gamma suppresses collagen-induced arthritis by regulation of Th17 through the induction of indoleamine-2,3-deoxygenase.
Response patterns of cytokines/chemokines in two murine strains after irradiation.
CCL25 induces α₄β₇ integrin-dependent migration of IL-17⁺ γδ T lymphocytes during an allergic reaction.
Hepatic interleukin-7 expression regulates T cell responses.
Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
Intestinal specific overexpression of interleukin-7 attenuates the alternation of intestinal intraepithelial lymphocytes after total parenteral nutrition administration.
Tumor-specific Th17-polarized cells eradicate large established melanoma.
A novel and sensitive ELISA reveals that the soluble form of IL-13R-alpha2 is not expressed in plasma of healthy or asthmatic subjects.
The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis.
The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis.
IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection.
IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection.
Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways.
Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways.
IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis.
IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis.
Lv R, Zhao J, Lei M, Xiao D, Yu Y, Xie J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(5):1961-1972
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(5):1961-1972
The Major Histocompatibility Complex Class III Haplotype Ltab-Ncr3 Regulates Adjuvant-Induced but Not Antigen-Induced Autoimmunity.
Yau ACY, Tuncel J, Holmdahl R
The American journal of pathology 2017 May;187(5):987-998
The American journal of pathology 2017 May;187(5):987-998
MHC class II alleles associated with Th1 rather than Th17 type immunity drive the onset of early arthritis in a rat model of rheumatoid arthritis.
Tuncel J, Haag S, Holmdahl R
European journal of immunology 2017 Mar;47(3):563-574
European journal of immunology 2017 Mar;47(3):563-574
Interferon-gamma regulates inflammatory cell death by targeting necroptosis in experimental autoimmune arthritis.
Lee SH, Kwon JY, Kim SY, Jung K, Cho ML
Scientific reports 2017 Aug 31;7(1):10133
Scientific reports 2017 Aug 31;7(1):10133
Enhanced immunoregulation of mesenchymal stem cells by IL-10-producing type 1 regulatory T cells in collagen-induced arthritis.
Lim JY, Im KI, Lee ES, Kim N, Nam YS, Jeon YW, Cho SG
Scientific reports 2016 Jun 1;6:26851
Scientific reports 2016 Jun 1;6:26851
Interferon gamma suppresses collagen-induced arthritis by regulation of Th17 through the induction of indoleamine-2,3-deoxygenase.
Lee J, Lee J, Park MK, Lim MA, Park EM, Kim EK, Yang EJ, Lee SY, Jhun JY, Park SH, Kim HY, Cho ML
PloS one 2013;8(4):e60900
PloS one 2013;8(4):e60900
Response patterns of cytokines/chemokines in two murine strains after irradiation.
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, Salzman P, Wang W, Liu C, Vidyasagar S, Zhang L, Ju S, Okunieff P, Zhang L
Cytokine 2012 May;58(2):169-77
Cytokine 2012 May;58(2):169-77
CCL25 induces α₄β₇ integrin-dependent migration of IL-17⁺ γδ T lymphocytes during an allergic reaction.
Costa MF, Bornstein VU, Candéa AL, Henriques-Pons A, Henriques MG, Penido C
European journal of immunology 2012 May;42(5):1250-60
European journal of immunology 2012 May;42(5):1250-60
Hepatic interleukin-7 expression regulates T cell responses.
Sawa Y, Arima Y, Ogura H, Kitabayashi C, Jiang JJ, Fukushima T, Kamimura D, Hirano T, Murakami M
Immunity 2009 Mar 20;30(3):447-57
Immunity 2009 Mar 20;30(3):447-57
Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA Jr, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 7;106(14):5954-9
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 7;106(14):5954-9
Intestinal specific overexpression of interleukin-7 attenuates the alternation of intestinal intraepithelial lymphocytes after total parenteral nutrition administration.
Yang H, Gumucio DL, Teitelbaum DH
Annals of surgery 2008 Nov;248(5):849-56
Annals of surgery 2008 Nov;248(5):849-56
Tumor-specific Th17-polarized cells eradicate large established melanoma.
Muranski P, Boni A, Antony PA, Cassard L, Irvine KR, Kaiser A, Paulos CM, Palmer DC, Touloukian CE, Ptak K, Gattinoni L, Wrzesinski C, Hinrichs CS, Kerstann KW, Feigenbaum L, Chan CC, Restifo NP
Blood 2008 Jul 15;112(2):362-73
Blood 2008 Jul 15;112(2):362-73
A novel and sensitive ELISA reveals that the soluble form of IL-13R-alpha2 is not expressed in plasma of healthy or asthmatic subjects.
O'Toole M, Legault H, Ramsey R, Wynn TA, Kasaian MT
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008 Apr;38(4):594-601
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008 Apr;38(4):594-601
The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis.
Sheibanie AF, Yen JH, Khayrullina T, Emig F, Zhang M, Tuma R, Ganea D
Journal of immunology (Baltimore, Md. : 1950) 2007 Jun 15;178(12):8138-47
Journal of immunology (Baltimore, Md. : 1950) 2007 Jun 15;178(12):8138-47
The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis.
Sheibanie AF, Yen JH, Khayrullina T, Emig F, Zhang M, Tuma R, Ganea D
Journal of immunology (Baltimore, Md. : 1950) 2007 Jun 15;178(12):8138-47
Journal of immunology (Baltimore, Md. : 1950) 2007 Jun 15;178(12):8138-47
IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection.
Lockhart E, Green AM, Flynn JL
Journal of immunology (Baltimore, Md. : 1950) 2006 Oct 1;177(7):4662-9
Journal of immunology (Baltimore, Md. : 1950) 2006 Oct 1;177(7):4662-9
IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection.
Lockhart E, Green AM, Flynn JL
Journal of immunology (Baltimore, Md. : 1950) 2006 Oct 1;177(7):4662-9
Journal of immunology (Baltimore, Md. : 1950) 2006 Oct 1;177(7):4662-9
Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways.
Miyamoto M, Prause O, Sjöstrand M, Laan M, Lötvall J, Lindén A
Journal of immunology (Baltimore, Md. : 1950) 2003 May 1;170(9):4665-72
Journal of immunology (Baltimore, Md. : 1950) 2003 May 1;170(9):4665-72
Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways.
Miyamoto M, Prause O, Sjöstrand M, Laan M, Lötvall J, Lindén A
Journal of immunology (Baltimore, Md. : 1950) 2003 May 1;170(9):4665-72
Journal of immunology (Baltimore, Md. : 1950) 2003 May 1;170(9):4665-72
IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis.
Lubberts E, Joosten LA, Oppers B, van den Bersselaar L, Coenen-de Roo CJ, Kolls JK, Schwarzenberger P, van de Loo FA, van den Berg WB
Journal of immunology (Baltimore, Md. : 1950) 2001 Jul 15;167(2):1004-13
Journal of immunology (Baltimore, Md. : 1950) 2001 Jul 15;167(2):1004-13
IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis.
Lubberts E, Joosten LA, Oppers B, van den Bersselaar L, Coenen-de Roo CJ, Kolls JK, Schwarzenberger P, van de Loo FA, van den Berg WB
Journal of immunology (Baltimore, Md. : 1950) 2001 Jul 15;167(2):1004-13
Journal of immunology (Baltimore, Md. : 1950) 2001 Jul 15;167(2):1004-13
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