Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Other assay [1]
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Validation data
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- Product number
- MA5-23738 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- IL-17A Monoclonal Antibody (41809)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- In direct ELISAs, approximately 12% cross-reactivity with recombinant canine IL-17 is observed and 25%-50% reactivity with recombinant human (rh) IL-17A/IL-17F heterodimer is observed. No cross-reactivity with recombinant mouse IL-17, rhIL-17B, rhIL-17C, rhIL-17D, rhIL-17E, or rhIL-17F is observed.
- Antibody clone number
- 41809
- Concentration
- 0.5 mg/mL
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Neutralization antibody testing demonstrates the specificity of an antibody through a correlation between antibody binding and the activity of the target. Neutralization of IL-17 is shown by the decrease in OD (IL-6 secretion by IL-17 stimulation is measured by IL-6 ELISA) with increasing concentrations of IL-17 Antibody (Product # MA5-23738).