326705

antibody from BioLegend

Targeting: FZD4 CD344, EVR1

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

326705

Provider

BioLegend

Product name

Alexa Fluor® 647 anti-human CD349 (Frizzled-9) [W3C4E11]

Antibody type

Monoclonal

Antigen

WERI-RB-1 retinoblastoma cells

Description

 CD349 is a member of the Frizzled family, known as Frizzled-9 (Fz9, FZD9, hFz9, or FzE6) which was originally described as FZD3. Ten frizzled member have been identified in humans. FZD9 is a seven transmembrane G-protein-coupled receptor (GPCR), a receptor for Wnt proteins. It is involved in the activation of Wnt/β-catenin pathway (canonic Wnt signaling). FZD9 is predominately expressed in fetal and adult brain, testis, eye, skeletal muscle and kidney and is also expressed on Mesenchymal stem cells, and neural precursor cells. Frizzled proteins play important roles in controlling cell fate, proliferation, migration, tissue architecture and organogenesis during embryonic development and in adult organisms. FZD9 is an important factor for nervous system development and is critical for hippocampal development.

Reactivity

Human

Host

Mouse

Conjugate

Red dye

Isotype

IgM

Vial size

25 tests

Storage

The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.