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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Product number
- NBP2-44404-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TRIM29 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. It recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Western Blot: TRIM29 Antibody (TRIM29/1042) [NBP2-44404] - TRIM29 Recombinant protein fragment & A431 Cell Lysate TRIM29 Monoclonal Antibody (TRIM29/1042).
