orb150826

antibody from Biorbyt

Targeting: SHANK1 SPANK-1, SSTRIP, synamon

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

orb150826

Provider

Biorbyt

Product name

SHANK1 antibody (ATTO-655)

Antibody type

Monoclonal

Description

Mouse monoclonal to SHANK1 (ATTO-655). SHANK proteins are scaffolding adaptors that have been shown to integrate neurotransmitter receptors into the cortical cytoskeleton at postsynaptic densities. SHANK1-3 of the SHANK/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). SHANK recruits betaPIX and PAK to dendritic spines to regulate postsynaptic structure and interacts with ionotropic receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development..

Reactivity

Rat

Host

Mouse

Isotype

IgG

Antibody clone number

S367-51

Vial size

100 μg

Concentration

1 mg/ml

Storage

Store at 2-8°C and -20°C for one year. (Shipped on ice packs)