Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1002283 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- FAF1 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human FAF1.
- Description
- Affinity chromatography purified via peptide column.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 1.
Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB.
Apoptosis induced by human Fas-associated factor 1, hFAF1, requires its ubiquitin homologous domain, but not the Fas-binding domain.
A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis.
Kinoshita T, Kondoh C, Hasegawa M, Imamura R, Suda T
International immunology 2006 Dec;18(12):1701-6
International immunology 2006 Dec;18(12):1701-6
Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB.
Park MY, Jang HD, Lee SY, Lee KJ, Kim E
The Journal of biological chemistry 2004 Jan 23;279(4):2544-9
The Journal of biological chemistry 2004 Jan 23;279(4):2544-9
Apoptosis induced by human Fas-associated factor 1, hFAF1, requires its ubiquitin homologous domain, but not the Fas-binding domain.
Ryu SW, Kim E
Biochemical and biophysical research communications 2001 Sep 7;286(5):1027-32
Biochemical and biophysical research communications 2001 Sep 7;286(5):1027-32
A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis.
Chu K, Niu X, Williams LT
Proceedings of the National Academy of Sciences of the United States of America 1995 Dec 5;92(25):11894-8
Proceedings of the National Academy of Sciences of the United States of America 1995 Dec 5;92(25):11894-8
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