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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB099P - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Leukotriene B4 R1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Recognizes human Leukotriene B4 R1 (5).
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models.
Expression of enzymes and receptors of the leukotriene pathway in human neuroblastoma promotes tumor survival and provides a target for therapy.
Residues from transmembrane helices 3 and 5 participate in leukotriene B4 binding to BLT1.
Sasaki F, Koga T, Ohba M, Saeki K, Okuno T, Ishikawa K, Nakama T, Nakao S, Yoshida S, Ishibashi T, Ahmadieh H, Kanavi MR, Hafezi-Moghadam A, Penninger JM, Sonoda KH, Yokomizo T
JCI insight 2018 Sep 20;3(18)
JCI insight 2018 Sep 20;3(18)
Expression of enzymes and receptors of the leukotriene pathway in human neuroblastoma promotes tumor survival and provides a target for therapy.
Sveinbjörnsson B, Rasmuson A, Baryawno N, Wan M, Pettersen I, Ponthan F, Orrego A, Haeggström JZ, Johnsen JI, Kogner P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Oct;22(10):3525-36
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Oct;22(10):3525-36
Residues from transmembrane helices 3 and 5 participate in leukotriene B4 binding to BLT1.
Sabirsh A, Bywater RP, Bristulf J, Owman C, Haeggström JZ
Biochemistry 2006 May 9;45(18):5733-44
Biochemistry 2006 May 9;45(18):5733-44
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Detection of Leukotriene B4 R1 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human Leukotriene B4 R1 PE-conjugated Monoclonal Antibody (Catalog # FAB099P) or (B) Mouse IgG1 Phycoerythrin Isotype Control (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.
