Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB1850P-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human NKp46/NCR1 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human NKp46/NCR1 in direct ELISAs and Western blots.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 195314
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Activated hepatic stellate cells impair NK cell anti-fibrosis capacity through a TGF-β-dependent emperipolesis in HBV cirrhotic patients.
Altered expression of miR-181a and miR-146a does not change the expression of surface NCRs in human NK cells.
Natural killer cells are characterized by the concomitantly increased interferon-γ and cytotoxicity in acute resolved hepatitis B patients.
Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil.
Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients.
Endometrial NK cells are special immature cells that await pregnancy.
Shi J, Zhao J, Zhang X, Cheng Y, Hu J, Li Y, Zhao X, Shang Q, Sun Y, Tu B, Shi L, Gao B, Wang FS, Zhang Z
Scientific reports 2017 Mar 14;7:44544
Scientific reports 2017 Mar 14;7:44544
Altered expression of miR-181a and miR-146a does not change the expression of surface NCRs in human NK cells.
Rady M, Watzl C, Claus M, Khorshid O, Mahran L, Abou-Aisha K
Scientific reports 2017 Feb 1;7:41381
Scientific reports 2017 Feb 1;7:41381
Natural killer cells are characterized by the concomitantly increased interferon-γ and cytotoxicity in acute resolved hepatitis B patients.
Zhao J, Li Y, Jin L, Zhang S, Fan R, Sun Y, Zhou C, Shang Q, Li W, Zhang Z, Wang FS
PloS one 2012;7(11):e49135
PloS one 2012;7(11):e49135
Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil.
Teixeira-Carvalho A, Fujiwara RT, Stemmy EJ, Olive D, Damsker JM, Loukas A, Corrêa-Oliveira R, Constant SL, Bethony JM
Infection and immunity 2008 Dec;76(12):5810-6
Infection and immunity 2008 Dec;76(12):5810-6
Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients.
Cai L, Zhang Z, Zhou L, Wang H, Fu J, Zhang S, Shi M, Zhang H, Yang Y, Wu H, Tien P, Wang FS
Clinical immunology (Orlando, Fla.) 2008 Dec;129(3):428-37
Clinical immunology (Orlando, Fla.) 2008 Dec;129(3):428-37
Endometrial NK cells are special immature cells that await pregnancy.
Manaster I, Mizrahi S, Goldman-Wohl D, Sela HY, Stern-Ginossar N, Lankry D, Gruda R, Hurwitz A, Bdolah Y, Haimov-Kochman R, Yagel S, Mandelboim O
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):1869-76
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):1869-76
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Detection of NKp46/NCR1 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A) and either (A) Mouse Anti-Human NKp46/NCR1 PE-conjugated Monoclonal Antibody (Catalog # FAB1850P) or (B) Mouse IgG2B Phycoerythrin Isotype Control (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins.