NBP2-47713JF646

antibody from Novus Biologicals

Targeting: CNN1 Sm-Calp, SMCC

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

NBP2-47713JF646

Provider

Novus Biologicals

Product name

Mouse Monoclonal Calponin 1 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified. Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle

Reactivity

Human, Rat

Host

Mouse

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.