Antibody data

Product number
orb76160 - Provider product page
Provider
Biorbyt
Product name
CTH antibody
Antibody type
Polyclonal
Description
Rabbit Polyclonal to CTH. CTH(CYSTATHIONINE GAMMA-LYASE),also called CYSTATHIONASE, is an enzyme which breaks down cystathionine into cysteine and alpha-ketobutyrate.And the CTH gene is mapped on 1p31.1. In some bacteria and mammals, including humans, this enzyme takes part in generating hydrogen sulfide and that genetic deletion of this enzyme in mice markedly reduced H2S levels in the serum, heart, aorta, and other tissues. Mutant mice lacking CTH displayed pronounced hypertension and diminished endothelium-dependent vasorelaxation. Cystathionine was physiologically activated by calcium and calmodulin, which is a mechanism for H2S formation in response to vascular activation.
Reactivity
Human, Rat
Host
Rabbit
Conjugate
Unconjugated
Vial size
100 μg
Concentration
0.1-0.5 μg/ml,0.5-1 μg/ml,0.5-1 μg/ml
Storage
Store at -20°C for one year.After reconstitution, at 4°C. for one month. It can also be aliquotted and stored frozen at -20°C. for a longer time.Avoid repeated freezing and thawing.
CTH protein structure - orb76160 shown in red.