Antibody data

Product number
302950 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#302950, RRID:AB_2632607
Product name
Brilliant Violet 785™ anti-human CD28
Antibody type
Monoclonal
Description
CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
Reactivity
Human, Porcine
Host
Mouse
Conjugate
Near infrared dye
Antibody clone number
CD28.2
Vial size
100 tests
Storage
2°C-8°C
Handling
Ambient RT
CD28 protein structure - 302950 shown in red.