330905

antibody from BioLegend
Targeting: CD58 LFA3
Provider product page for 330905

Antibody data

Product number
330905 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#330905, RRID:AB_1186063
Product name
PE anti-human CD58 (LFA-3)
Antibody type
Monoclonal
Antigen
Human cytolytic T cells
Description
CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface. The HCD58 antibody recognizes human CD58 and has been shown to be useful for flow cytometry.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CD58 protein structure - 330905 shown in red.