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- Antibody Data
- Antigen structure
- References [3]
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- Product number
- BAF1830 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal IL-6R alpha Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse IL-6R alpha in ELISAs and Western blots. In sandwich ELISAs, less than 1% cross-reactivity with recombinant human IL-6R, recombinant mouse (rm) IL-6, and rmgp130 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Biotin
- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils.
Sequential ELISA to profile multiple cytokines from small volumes.
Rabe B, Chalaris A, May U, Waetzig GH, Seegert D, Williams AS, Jones SA, Rose-John S, Scheller J
Blood 2008 Feb 1;111(3):1021-8
Blood 2008 Feb 1;111(3):1021-8
Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils.
Chalaris A, Rabe B, Paliga K, Lange H, Laskay T, Fielding CA, Jones SA, Rose-John S, Scheller J
Blood 2007 Sep 15;110(6):1748-55
Blood 2007 Sep 15;110(6):1748-55
Sequential ELISA to profile multiple cytokines from small volumes.
Osuchowski MF, Siddiqui J, Copeland S, Remick DG
Journal of immunological methods 2005 Jul;302(1-2):172-81
Journal of immunological methods 2005 Jul;302(1-2):172-81
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