CABT-BL7502

antibody from Creative Diagnostics
Targeting: FCER1A FCE1A
Provider product page for CABT-BL7502
No application information provided.

Antibody data

Product number
CABT-BL7502 - Provider product page
Provider
Creative Diagnostics
Product name
Anti-Fcer1a Monoclonal antibody, clone NBS-2 [PE]
Antibody type
Monoclonal
Description
The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta ., and gamma .
FCER1A protein structure - CABT-BL7502 shown in red.