AGTO-L015R

antibody from Creative Biolabs

Targeting: FCER1G

Functional assay (Recommended by provider)

Antibody Data

Product number

AGTO-L015R

Provider

Creative Biolabs

Product name

anti-Fcer1g immunotoxin 84.1C (IgG)-RTA

Antibody type

Monoclonal

Description

This immunotoxin was achieved by conjugating/fusing the Anti-Fcer1g monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to surface IgE-expressing cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of periodic (seasonal) allergic.

Reactivity

Mouse

Host

Rat

Antibody clone number

84.1C