NB100-64346AF405

antibody from Novus Biologicals
Targeting: FCGR3A CD16, CD16a, FCG3, FCGR3
Provider product page for NB100-64346AF405
Immunohistochemistry
Flow cytometry

Antibody data

Product number
NB100-64346AF405 - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal Fc gamma RIIIA/CD16a Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. NB100-64346 recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. DJ130c recognizes all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the DJ130c antibody recognizes an epitope in the first membrane-distal domain of CD16 and recognizes both CD16A and CD16B.
Reactivity
Human
Host
Mouse
Conjugate
Blue dye
Isotype
IgG
Vial size
0.1 ml
Storage
Store at 4C in the dark.
FCGR3A protein structure - NB100-64346AF405 shown in red.