ABIN362425

antibody from antibodies-online

Targeting: NTRK2 TRKB

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN362425

Provider

antibodies-online

Product name

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (pTyr705) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pTyr705 (T-D-Y P-Y-R) derived from Human TrkB. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pTyr705

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Sex-dependent alterations in BDNF-TrkB signaling in the hippocampus of reelin heterozygous mice: a role for sex steroid hormones.

Hill RA, Wu YW, Gogos A, van den Buuse M
Journal of neurochemistry 2013 Aug;126(3):389-99

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Sex-dependent and region-specific changes in TrkB signaling in BDNF heterozygous mice.

Hill RA, van den Buuse M
Brain research 2011 Apr 12;1384:51-60

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Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase.

Woronowicz A, Amith SR, De Vusser K, Laroy W, Contreras R, Basta S, Szewczuk MR
Glycobiology 2007 Jan;17(1):10-24

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Protecting motor neurons from toxic insult by antagonism of adenosine A2a and Trk receptors.

Mojsilovic-Petrovic J, Jeong GB, Crocker A, Arneja A, David S, Russell DS, Kalb RG
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Sep 6;26(36):9250-63

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BDNF-mediated enhancement of inflammation and injury in the aging heart.

Cai D, Holm JM, Duignan IJ, Zheng J, Xaymardan M, Chin A, Ballard VL, Bella JN, Edelberg JM
Physiological genomics 2006 Feb 14;24(3):191-7

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Identification and characterization of compounds that potentiate NT-3-mediated Trk receptor activity.

Lewis MA, Hunihan L, Franco D, Robertson B, Palmer J, Laurent DR, Balasubramanian BN, Li Y, Westphal RS
Molecular pharmacology 2006 Apr;69(4):1396-404