Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB689F-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human GITR/TNFRSF18 Fluorescein-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human GITR in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) 4-1BB, recombinant mouse (rm) 4-1BB, rhCD27, rmCD27, rhCD30, rmCD30, rhCD40, rmCD40, rhDR3, rhDR6, rhEDAR, rmEDAR, rhFas, rmFAS, rmGITR, rhHVEM, rhLymphotoxin R beta , rmLymphotoxin R beta , rhNGF R, rhOPG, rmOPG, rhRANK, rmRANK, rhTAJ, rhTNF RI, rmTNF RI, rhTNF RII, or rmTNF RII.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
Q9Y5U5
- Isotype
- IgG
- Antibody clone number
- 110416
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Stem cell source-dependent reconstitution of FOXP3+ T cells after pediatric SCT and the association with allo-reactive disease.
Expression of the T cell receptor αβ on a CD123+ BDCA2+ HLA-DR+ subpopulation in head and neck squamous cell carcinoma.
Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells.
CD4+CD25high T cell numbers are enriched in the peripheral blood of patients with rheumatoid arthritis.
Reubsaet LL, de Pagter AP, van Baarle D, Keukens L, Nanlohy N, Sanders EA, Prakken BJ, Boelens JJ, de Kleer IM
Bone marrow transplantation 2013 Apr;48(4):502-7
Bone marrow transplantation 2013 Apr;48(4):502-7
Expression of the T cell receptor αβ on a CD123+ BDCA2+ HLA-DR+ subpopulation in head and neck squamous cell carcinoma.
Thiel A, Kesselring R, Pries R, Puzik A, Wittkopf N, Wollenberg B
PloS one 2011 Jan 11;6(1):e15997
PloS one 2011 Jan 11;6(1):e15997
Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells.
Mandapathil M, Hilldorfer B, Szczepanski MJ, Czystowska M, Szajnik M, Ren J, Lang S, Jackson EK, Gorelik E, Whiteside TL
The Journal of biological chemistry 2010 Mar 5;285(10):7176-86
The Journal of biological chemistry 2010 Mar 5;285(10):7176-86
CD4+CD25high T cell numbers are enriched in the peripheral blood of patients with rheumatoid arthritis.
Han GM, O'Neil-Andersen NJ, Zurier RB, Lawrence DA
Cellular immunology 2008 May-Jun;253(1-2):92-101
Cellular immunology 2008 May-Jun;253(1-2):92-101
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of GITR/TNFRSF18 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) treated with 1 μg/mL PHA for 24 hours were stained with Mouse Anti-Human GITR/TNFRSF18 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB689F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins.