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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 339512 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#339512, RRID:AB_2565579
- Product name
- PE/Cy7 anti-human CD158 (KIR2DL1/S1/S3/S5)
- Antibody type
- Monoclonal
- Antigen
- Human NK cell clone LB2
- Description
- CD158 molecules, also known as KIRs (killer cell immunoglobulin-like receptors), are a family of transmembrane proteins with either two (KIR2D) or three (KIR3D) Ig-like extracellular domains. Some KIRs with long cytoplasmic domains contain ITIMs and posses inhibitory functions and others with short cytoplasmic region lack ITIM and have activation functions. 14 polymorphic KIR genes have been reported in humans. CD158 is mainly expressed on a subset of NK cells and a small population of CD8+ T cells. HLA-C is the ligand of CD158a/h.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Near infrared dye
- Antibody clone number
- HP-MA4
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human peripheral blood lymphocytes were stained with CD56 Alexa Fluor® 488 and CD158 (clone HP-MA4) PE/Cy7 (top) or mouse IgG2b, κ PE/Cy7 isotype control (bottom).
- Conjugate
- Near infrared dye
