orb148605

antibody from Biorbyt

Targeting: SHANK2 CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

orb148605

Provider

Biorbyt

Product name

SHANK2 antibody (HRP)

Antibody type

Monoclonal

Description

Mouse monoclonal to SHANK2 (HRP). Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Studies suggest that Shank2 is expressed in the neurons of the developing retina, and could play a role in the neuronal differentiation of the developing retina. Other recent studies suggest that the disruption of glutamate receptors at the Shank postsynaptic platform could contribute to the destruction of the postsynaptic density, which underlies the synaptic dysfunction and loss in Alzheimers disease..

Reactivity

Human, Rat

Host

Mouse

Conjugate

Horseradish Peroxidase

Isotype

IgG

Antibody clone number

S23b-6

Vial size

100 μg

Concentration

1 mg/ml

Storage

Store at 2-8°C and -20°C for one year. (Shipped on ice packs)