CABT-BL8076

antibody from Creative Diagnostics

Targeting: MCAM CD146, HEMCAM, MelCAM, METCAM, MUC18

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL8076

Provider

Creative Diagnostics

Product name

Anti-MCAM Monoclonal antibody, clone Q2I23 [PE]

Antibody type

Monoclonal

Description

MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Reactivity

Human, Mouse, Canine, Rabbit

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG