342006

antibody from BioLegend

Targeting: MCAM CD146, HEMCAM, MelCAM, METCAM, MUC18

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

342006

Provider

BioLegend

Proper citation

BioLegend Cat#342006, RRID:AB_1595423

Product name

Alexa Fluor® 647 anti-human CD146 (MUC18, Mel-CAM) [SHM-57]

Antibody type

Monoclonal

Antigen

CD146

Description

CD146 is a 118 kD integral transmembrane glycoprotein also known as MUC18, S-Endo, MCAM, and Mel-CAM (melanoma cell adhesion molecule). It belongs to the immunoglobulin superfamily. CD146 is expressed on melanoma cells, epithelial cells, endothelial cells, fibroblasts, activated T cells, multipotent mesenchymal stromal cells, and activated keratinocytes. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration. The ligand of CD146 remains to be identified.

Reactivity

Human

Host

Mouse

Conjugate

Red dye

Isotype

IgG

Vial size

100 tests

Storage

The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.