ABIN1002726

antibody from antibodies-online

Targeting: LGI3

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN1002726

Provider

antibodies-online

Product name

anti-Leucine-Rich Repeat LGI Family, Member 3 (LGI3) (Internal Region) antibody

Antibody type

Polyclonal

Antigen

LGI3 antibody was raised in rabbits against a 12 amino acid peptide from near the center of human LGI3.

Description

Affinity chromatography purified via peptide column.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Internal Region

Isotype

IgG

Vial size

100 μg

Storage

4°C

Handling

Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.

References

Submitted references

Abeta upregulates and colocalizes with LGI3 in cultured rat astrocytes.

Kimura N, Ishii Y, Suzaki S, Negishi T, Kyuwa S, Yoshikawa Y
Cellular and molecular neurobiology 2007 May;27(3):335-50

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Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders.

Gu W, Gibert Y, Wirth T, Elischer A, Bloch W, Meyer A, Steinlein OK, Begemann G
Molecular biology and evolution 2005 Nov;22(11):2209-16

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LGI1 mutations in temporal lobe epilepsies.

Berkovic SF, Izzillo P, McMahon JM, Harkin LA, McIntosh AM, Phillips HA, Briellmann RS, Wallace RH, Mazarib A, Neufeld MY, Korczyn AD, Scheffer IE, Mulley JC
Neurology 2004 Apr 13;62(7):1115-9

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A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors.

Chernova OB, Somerville RP, Cowell JK
Oncogene 1998 Dec 3;17(22):2873-81