CABT-BL7736

antibody from Creative Diagnostics

Targeting: IL17RA CD217, CDw217, hIL-17R, IL-17RA, IL17R

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL7736

Provider

Creative Diagnostics

Product name

Anti-IL17RA Monoclonal antibody, clone K20NCT [PE]

Antibody type

Monoclonal

Description

Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.

Reactivity

Human

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG