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Western blot
Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Blocking/Neutralizing [1]
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- Product number
- MAB1211 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Growth Hormone R Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects rat Growth Hormone R/GHR in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant human GHR is observed, but no cross-reactivity with recombinant mouse GHR is observed.
- Reactivity
- Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 500 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Growth Hormone R/GHR Inhibition of Growth Hormone-dependent Cell Proliferation and Neutralization by Rat Growth Hormone R/GHR Antibody. Recombinant Rat Growth Hormone R/GHR Fc Chimera (Catalog # 1211-GR) inhibits Recom-binant Human Growth Hormone (Catalog # 1067-GH) induced prolifer-ation in the Nb2-11 rat lymphoma cell line in a dose-dependent manner (orange line). Inhibition of Recom-binant Human Growth Hormone (0.2 ng/mL) activity elicited by Recom-binant Rat Growth Hormone R/GHR Fc Chimera (10 ng/mL) is neutralized (green line) by increasing concent-rations of Mouse Anti-Rat Growth Hormone R/GHR Mono-clonal Antibody (Catalog # MAB1211). The ND50 is typically 0.9-3.6 µg/mL.
