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- Antibody Data
- Antigen structure
- References [6]
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- Product number
- BAF856 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse IL-18 R alpha/IL-1 R5 Biotinylated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse IL-18 R alpha/IL-1 R5 in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human IL-18 R is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Biotin
- Antigen sequence
Q61098- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling.
Protection of CD8+ T cells from activation-induced cell death by IL-18.
DAP12 signaling directly augments proproliferative cytokine stimulation of NK cells during viral infections.
DAP12 signaling directly augments proproliferative cytokine stimulation of NK cells during viral infections.
Distinct modulatory effects of LPS and CpG on IL-18-dependent IFN-gamma synthesis.
Distinct modulatory effects of LPS and CpG on IL-18-dependent IFN-gamma synthesis.
Nold-Petry CA, Nold MF, Nielsen JW, Bustamante A, Zepp JA, Storm KA, Hong JW, Kim SH, Dinarello CA
The Journal of biological chemistry 2009 Sep 18;284(38):25900-11
The Journal of biological chemistry 2009 Sep 18;284(38):25900-11
Protection of CD8+ T cells from activation-induced cell death by IL-18.
Li W, Kashiwamura S, Ueda H, Sekiyama A, Okamura H
Journal of leukocyte biology 2007 Jul;82(1):142-51
Journal of leukocyte biology 2007 Jul;82(1):142-51
DAP12 signaling directly augments proproliferative cytokine stimulation of NK cells during viral infections.
French AR, Sjölin H, Kim S, Koka R, Yang L, Young DA, Cerboni C, Tomasello E, Ma A, Vivier E, Kärre K, Yokoyama WM
Journal of immunology (Baltimore, Md. : 1950) 2006 Oct 15;177(8):4981-90
Journal of immunology (Baltimore, Md. : 1950) 2006 Oct 15;177(8):4981-90
DAP12 signaling directly augments proproliferative cytokine stimulation of NK cells during viral infections.
French AR, Sjölin H, Kim S, Koka R, Yang L, Young DA, Cerboni C, Tomasello E, Ma A, Vivier E, Kärre K, Yokoyama WM
Journal of immunology (Baltimore, Md. : 1950) 2006 Oct 15;177(8):4981-90
Journal of immunology (Baltimore, Md. : 1950) 2006 Oct 15;177(8):4981-90
Distinct modulatory effects of LPS and CpG on IL-18-dependent IFN-gamma synthesis.
Gould MP, Greene JA, Bhoj V, DeVecchio JL, Heinzel FP
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 1;172(3):1754-62
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 1;172(3):1754-62
Distinct modulatory effects of LPS and CpG on IL-18-dependent IFN-gamma synthesis.
Gould MP, Greene JA, Bhoj V, DeVecchio JL, Heinzel FP
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 1;172(3):1754-62
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 1;172(3):1754-62
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