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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB840A-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-18 R alpha/IL-1 R5 APC-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human IL-18 R alpha/IL-1 R5 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-1 RI, rhIL-1 RII, rhIL-1 R3, rhIL-1 R4, rhIL-1 R6, rhIL-1 R7, rhIL-1 R8, rhIL-1 R9, rhSIGIRR or recombinant mouse IL-18 R alpha is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antigen sequence
Q13478- Isotype
- IgG
- Antibody clone number
- 70625
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Altered expression of IL-18 binding protein and IL-18 receptor in basophils and mast cells of asthma patients.
Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R.
Enhanced Expression of IL-18 and IL-18BP in Plasma of Patients with Eczema: Altered Expression of IL-18BP and IL-18 Receptor on Mast Cells.
Wang Z, Liu Z, Wang L, Wang J, Chen L, Xie H, Zhang H, He S
Scandinavian journal of immunology 2018 May;87(5):e12658
Scandinavian journal of immunology 2018 May;87(5):e12658
Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R.
Zhang H, Wang J, Wang L, Xie H, Chen L, He S
Journal of cellular and molecular medicine 2018 Jan;22(1):354-373
Journal of cellular and molecular medicine 2018 Jan;22(1):354-373
Enhanced Expression of IL-18 and IL-18BP in Plasma of Patients with Eczema: Altered Expression of IL-18BP and IL-18 Receptor on Mast Cells.
Hu Y, Wang J, Zhang H, Xie H, Song W, Jiang Q, Zhao N, He S
Mediators of inflammation 2017;2017:3090782
Mediators of inflammation 2017;2017:3090782
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of IL-18 R alpha/IL-1 R5 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) treated with PHA (5 μg/ml) and Recombinant Human IL-2 (Catalog # 202-IL;10 ng/ml) for 2 days were stained with Mouse Anti-Human IL-18 R alpha/IL-1 R5 APC-conjugated Monoclonal Antibody (Catalog # FAB840A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.
