313810

antibody from BioLegend
Targeting: IL18R1 CD218a, IL-1Rrp, IL1RRP
Provider product page for 313810

Antibody data

Product number
313810 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#313810, RRID:AB_2123648
Product name
FITC anti-human CD218a (IL-18R‡)
Antibody type
Monoclonal
Antigen
Human NK cell line NK0 constitutively expressing IL-18 receptors
Description
IL-18 receptor is composed of an α and a β subunit that combine to form a high affinity receptor for IL-18. IL-18 receptor α chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis. The H44 antibody is specific for IL-18 receptor α chain and has been reported to block IL-18 binding to the receptor and to be useful for the identification of IL-18 receptor by flow cytometry and IHC.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
IL18R1 protein structure - 313810 shown in red.