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- Antibody Data
- Antigen structure
- References [29]
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- Immunohistochemistry [1]
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- Product number
- ABIN786762 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CD207 Molecule, Langerin (CD207) antibody (Biotin)
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- DCGM4-122D5-03
- Vial size
- 50 μg
Submitted references Inhibition of two temporal phases of HIV-1 transfer from primary Langerhans cells to T cells: the role of langerin.
Rosiglitazone promotes the differentiation of Langerhans cells and inhibits that of other dendritic cell types from CD133 positive hematopoietic precursors.
Human embryonic epidermis contains a diverse Langerhans cell precursor pool.
Generation of multipotent early lymphoid progenitors from human embryonic stem cells.
Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance.
Impact of smoking on dendritic cell phenotypes in the airway lumen of patients with COPD.
Birbeck granule-like "organized smooth endoplasmic reticulum" resulting from the expression of a cytoplasmic YFP-tagged langerin.
Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism.
Fluticasone impact on airway dendritic cells in smokers: a randomized controlled trial.
Comparative histology and immunohistochemistry of porcine versus human skin.
E-cadherin interactions are required for Langerhans cell differentiation.
Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo.
Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.
Age-related changes in expression and function of Toll-like receptors in human skin.
Distribution and maturation of skin dendritic cell subsets in two forms of cutaneous T-cell lymphoma: mycosis fungoides and Sézary syndrome.
Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells.
Characterization of resident and migratory dendritic cells in human lymph nodes.
Human Langerhans cells capture measles virus through Langerin and present viral antigens to CD4⁺ T cells but are incapable of cross-presentation.
Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T-cell subsets.
Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-β1-dependent human epidermal Langerhans cells.
Technical advance: Langerhans cells derived from a human cell line in a full-thickness skin equivalent undergo allergen-induced maturation and migration.
HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies.
Glucocorticosteroids modify Langerhans cells to produce TGF-β and expand regulatory T cells.
The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency.
Acute ablation of Langerhans cells enhances skin immune responses.
A nonredundant role for canonical NF-κB in human myeloid dendritic cell development and function.
Herpes simplex virus type 2 enhances HIV-1 susceptibility by affecting Langerhans cell function.
Impact of varicella-zoster virus on dendritic cell subsets in human skin during natural infection.
Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules.
Nasr N, Lai J, Botting RA, Mercier SK, Harman AN, Kim M, Turville S, Center RJ, Domagala T, Gorry PR, Olbourne N, Cunningham AL
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 1;193(5):2554-64
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 1;193(5):2554-64
Rosiglitazone promotes the differentiation of Langerhans cells and inhibits that of other dendritic cell types from CD133 positive hematopoietic precursors.
Bonetti MI, Bacci S, Santosuosso M, Mazzanti B, Aldinucci A, Ballerini C, Guasti D, Calosi L, Bosi A, Romagnoli P
Histology and histopathology 2014 Mar;29(3):323-32
Histology and histopathology 2014 Mar;29(3):323-32
Human embryonic epidermis contains a diverse Langerhans cell precursor pool.
Schuster C, Mildner M, Mairhofer M, Bauer W, Fiala C, Prior M, Eppel W, Kolbus A, Tschachler E, Stingl G, Elbe-Bürger A
Development (Cambridge, England) 2014 Feb;141(4):807-15
Development (Cambridge, England) 2014 Feb;141(4):807-15
Generation of multipotent early lymphoid progenitors from human embryonic stem cells.
Larbi A, Mitjavila-Garcia MT, Flamant S, Valogne Y, Clay D, Usunier B, l'Homme B, Féraud O, Casal I, Gobbo E, Divers D, Chapel A, Turhan AG, Bennaceur-Griscelli A, Haddad R
Stem cells and development 2014 Dec 15;23(24):2983-95
Stem cells and development 2014 Dec 15;23(24):2983-95
Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance.
Flacher V, Tripp CH, Mairhofer DG, Steinman RM, Stoitzner P, Idoyaga J, Romani N
EMBO molecular medicine 2014 Aug 1;6(9):1191-204
EMBO molecular medicine 2014 Aug 1;6(9):1191-204
Impact of smoking on dendritic cell phenotypes in the airway lumen of patients with COPD.
Stoll P, Heinz AS, Bratke K, Bier A, Garbe K, Kuepper M, Virchow JC, Lommatzsch M
Respiratory research 2014 Apr 18;15:48
Respiratory research 2014 Apr 18;15:48
Birbeck granule-like "organized smooth endoplasmic reticulum" resulting from the expression of a cytoplasmic YFP-tagged langerin.
Lenormand C, Spiegelhalter C, Cinquin B, Bardin S, Bausinger H, Angénieux C, Eckly A, Proamer F, Wall D, Lich B, Tourne S, Hanau D, Schwab Y, Salamero J, de la Salle H
PloS one 2013;8(4):e60813
PloS one 2013;8(4):e60813
Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism.
Welty NE, Staley C, Ghilardi N, Sadowsky MJ, Igyártó BZ, Kaplan DH
The Journal of experimental medicine 2013 Sep 23;210(10):2011-24
The Journal of experimental medicine 2013 Sep 23;210(10):2011-24
Fluticasone impact on airway dendritic cells in smokers: a randomized controlled trial.
Lommatzsch M, Kraeft U, Troebs L, Garbe K, Bier A, Stoll P, Klammt S, Kuepper M, Bratke K, Virchow JC
Respiratory research 2013 Oct 29;14:114
Respiratory research 2013 Oct 29;14:114
Comparative histology and immunohistochemistry of porcine versus human skin.
Debeer S, Le Luduec JB, Kaiserlian D, Laurent P, Nicolas JF, Dubois B, Kanitakis J
European journal of dermatology : EJD 2013 Jul-Aug;23(4):456-66
European journal of dermatology : EJD 2013 Jul-Aug;23(4):456-66
E-cadherin interactions are required for Langerhans cell differentiation.
Mayumi N, Watanabe E, Norose Y, Watari E, Kawana S, Geijtenbeek TB, Takahashi H
European journal of immunology 2013 Jan;43(1):270-80
European journal of immunology 2013 Jan;43(1):270-80
Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo.
Luckashenak N, Wähe A, Breit K, Brakebusch C, Brocker T
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):27-35
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):27-35
Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.
Hitzler M, Majdic O, Heine G, Worm M, Ebert G, Luch A, Peiser M
PloS one 2012;7(10):e46776
PloS one 2012;7(10):e46776
Age-related changes in expression and function of Toll-like receptors in human skin.
Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, Schöppl A, Tschachler E, Elbe-Bürger A
Development (Cambridge, England) 2012 Nov;139(22):4210-9
Development (Cambridge, England) 2012 Nov;139(22):4210-9
Distribution and maturation of skin dendritic cell subsets in two forms of cutaneous T-cell lymphoma: mycosis fungoides and Sézary syndrome.
Schwingshackl P, Obermoser G, Nguyen VA, Fritsch P, Sepp N, Romani N
Acta dermato-venereologica 2012 May;92(3):269-75
Acta dermato-venereologica 2012 May;92(3):269-75
Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells.
Haniffa M, Shin A, Bigley V, McGovern N, Teo P, See P, Wasan PS, Wang XN, Malinarich F, Malleret B, Larbi A, Tan P, Zhao H, Poidinger M, Pagan S, Cookson S, Dickinson R, Dimmick I, Jarrett RF, Renia L, Tam J, Song C, Connolly J, Chan JK, Gehring A, Bertoletti A, Collin M, Ginhoux F
Immunity 2012 Jul 27;37(1):60-73
Immunity 2012 Jul 27;37(1):60-73
Characterization of resident and migratory dendritic cells in human lymph nodes.
Segura E, Valladeau-Guilemond J, Donnadieu MH, Sastre-Garau X, Soumelis V, Amigorena S
The Journal of experimental medicine 2012 Apr 9;209(4):653-60
The Journal of experimental medicine 2012 Apr 9;209(4):653-60
Human Langerhans cells capture measles virus through Langerin and present viral antigens to CD4⁺ T cells but are incapable of cross-presentation.
van der Vlist M, de Witte L, de Vries RD, Litjens M, de Jong MA, Fluitsma D, de Swart RL, Geijtenbeek TB
European journal of immunology 2011 Sep;41(9):2619-31
European journal of immunology 2011 Sep;41(9):2619-31
Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T-cell subsets.
Fujita H, Shemer A, Suárez-Fariñas M, Johnson-Huang LM, Tintle S, Cardinale I, Fuentes-Duculan J, Novitskaya I, Carucci JA, Krueger JG, Guttman-Yassky E
The Journal of allergy and clinical immunology 2011 Sep;128(3):574-82.e1-12
The Journal of allergy and clinical immunology 2011 Sep;128(3):574-82.e1-12
Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-β1-dependent human epidermal Langerhans cells.
Eisenwort G, Jurkin J, Yasmin N, Bauer T, Gesslbauer B, Strobl H
The Journal of investigative dermatology 2011 Oct;131(10):2049-57
The Journal of investigative dermatology 2011 Oct;131(10):2049-57
Technical advance: Langerhans cells derived from a human cell line in a full-thickness skin equivalent undergo allergen-induced maturation and migration.
Ouwehand K, Spiekstra SW, Waaijman T, Scheper RJ, de Gruijl TD, Gibbs S
Journal of leukocyte biology 2011 Nov;90(5):1027-33
Journal of leukocyte biology 2011 Nov;90(5):1027-33
HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies.
Peressin M, Holl V, Schmidt S, Decoville T, Mirisky D, Lederle A, Delaporte M, Xu K, Aubertin AM, Moog C
Journal of virology 2011 Jan;85(2):1077-85
Journal of virology 2011 Jan;85(2):1077-85
Glucocorticosteroids modify Langerhans cells to produce TGF-β and expand regulatory T cells.
Stary G, Klein I, Bauer W, Koszik F, Reininger B, Kohlhofer S, Gruber K, Skvara H, Jung T, Stingl G
Journal of immunology (Baltimore, Md. : 1950) 2011 Jan 1;186(1):103-12
Journal of immunology (Baltimore, Md. : 1950) 2011 Jan 1;186(1):103-12
The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency.
Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Dimmick I, Chua I, Wallis J, Lordan J, Morgan C, Kumararatne DS, Doffinger R, van der Burg M, van Dongen J, Cant A, Dick JE, Hambleton S, Collin M
The Journal of experimental medicine 2011 Feb 14;208(2):227-34
The Journal of experimental medicine 2011 Feb 14;208(2):227-34
Acute ablation of Langerhans cells enhances skin immune responses.
Bobr A, Olvera-Gomez I, Igyarto BZ, Haley KM, Hogquist KA, Kaplan DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Oct 15;185(8):4724-8
Journal of immunology (Baltimore, Md. : 1950) 2010 Oct 15;185(8):4724-8
A nonredundant role for canonical NF-κB in human myeloid dendritic cell development and function.
van de Laar L, van den Bosch A, van der Kooij SW, Janssen HL, Coffer PJ, van Kooten C, Woltman AM
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 15;185(12):7252-61
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 15;185(12):7252-61
Herpes simplex virus type 2 enhances HIV-1 susceptibility by affecting Langerhans cell function.
de Jong MA, de Witte L, Taylor ME, Geijtenbeek TB
Journal of immunology (Baltimore, Md. : 1950) 2010 Aug 1;185(3):1633-41
Journal of immunology (Baltimore, Md. : 1950) 2010 Aug 1;185(3):1633-41
Impact of varicella-zoster virus on dendritic cell subsets in human skin during natural infection.
Huch JH, Cunningham AL, Arvin AM, Nasr N, Santegoets SJ, Slobedman E, Slobedman B, Abendroth A
Journal of virology 2010 Apr;84(8):4060-72
Journal of virology 2010 Apr;84(8):4060-72
Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules.
Valladeau J, Ravel O, Dezutter-Dambuyant C, Moore K, Kleijmeer M, Liu Y, Duvert-Frances V, Vincent C, Schmitt D, Davoust J, Caux C, Lebecque S, Saeland S
Immunity 2000 Jan;12(1):71-81
Immunity 2000 Jan;12(1):71-81
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